Endocrine Abstracts

Introduction: The pheochromocytomas are rare neuroendocrine tumors that can occur sporadically or, in about 30% of cases, in the context of family syndromes. Ten percent are malignant. Neurofibromatosis type 1 is an autosomal dominant disease that is associated with the occurrence of these tumors. Pheochromocytoma appears at 0.1– 5.7% of patients with neurofibromatosis type 1, and are usually solitary and benign lesions.Clinical case: A 50-year-old ...

Introduction: The adrenal ganglioneuroma are rare, benign and well differentiated tumors that arise from neural crest tissue. Most patients with adrenal ganglioneuroma are asymptomatic, and most of these are non-secreting tumors. They are usually found incidentally on abdominal imaging study for another reason.Case: A 53-year-old female, with a history of hypertension diagnosed at age 30, dyslipidaemia, depressive disorder and hysterectomy for uterine pr...

Introduction: Quality of life (QoL) is a subject of increasing interest in the health context. Applied to a chronic condition like diabetes, this issue could give an overall perspective of the health outcome.Objective: To evaluate the coping mechanisms, the treatment issues and its contribution to QoL of diabetes patients.Patients and methods: We gathered a sample of 94 diabetic subjects, 50% males, 55.3% type 1, with a mean age of...

Introduction: Maturity-Onset Diabetes of the Young (MODY) is a form of monogenic diabetes caused by mutations in islet-related genes characterized by early-onset and inheritance in an autosomal dominant manner. MODY accounts for 2 to 5% of all cases of diabetes. The clinical presentation is heterogenous. Our aim was to characterize clinical features of patients with MODY in our department.Methods: We retrospectively analysed MODY diabetes cases diagnosed...

Introduction: Bariatric surgery (BS) candidates display several nutritional deficiencies that can aggravate after surgery. Metabolic syndrome (MS) is a cluster of cardiovascular risk factors with several disturbed metabolic pathways. Therefore, individuals with MS submitted to BS are probably more prone to nutritional deficiencies.Objective: To evaluate the prevalence of nutritional deficiencies and eventual differences between BS candidates with and wit...

Background: Sleeve gastrectomy (SG) has effective results on weight loss, which should result from fat mass loss and efforts should be made to preserve lean mass. Few studies have evaluated body composition (BC) changes after SG for periods >2 years.Objective: To investigate the impact of SG on weight and BC, comparing by gender.Materials and methods: Retrospectively, databases of patients who underwent SG between 2011 and 2013...

Introduction: Few studies have evaluated the impact of type 2 diabetes on the prognosis of acute heart failure (HF). This study assessed the effect of diabetes and glycemic control on complications, hospital stay and prognosis in patients with acute HF.Methods: Retrospectively, databases of 428 hospitalized patients by acute HF were analyzed, 201 diabetic patients and 227 controls. Statistical analysis was done using SPSS, considering statistical signifi...

Background: Gastric Bypass surgery (Bypass) is recognized as the ultimate metabolic surgery. The success in type 2 Diabetes (DM2) remission documented in patients submitted to Vertical Sleeve Gastrectomy (Sleeve) made questionable the hypothesis that this restrictive surgery has beneficial metabolic effects.Main goal: Comparing the Bypass and Sleeve’s efficacy in DM2 remission.Methods: Retrospective study of 112 diabetic patie...

*These authors contributed equally to this workIntroductionThe prevalence of obesity has risen dramatically worldwide in the last three decades. Due to this obesity pandemic, a growing demand for weight-loss drugs has emerged. The increased use of these drugs has consequently lead to an increase in the report of adverse reactions.Case reportA 45-year-old woman with past medical history ...

Introduction: Ultrasound-guided fine-needle aspiration cytology (US-FNAC), the gold standard method to distinguish benign from malignant thyroid nodules, is the most accurate, cost-effective and minimal invasive preoperative test, aiming to resolve patient management. However, up to 30% of US-FNACs are classified as indeterminate nodules, making difficult to avoid unnecessary surgeries. Molecular tests may contribute to refine the preoperative diagnosis of thyroid nodules....